Tuesday, May 3, 2011

Acid Reflux Disease And Cancer

Acid reflux or gerd (gastroesophageal reflux disease) is a condition in which fluid splashes up from the stomach into the esophagus. This fluid contains mostly acid with some pepsin and bile. All three of these fluids are potentially dangerous to the sensitive esophageal tissue, with acid being the most harmful. This refluxed fluid can inflame and damage the lining of the esophagus (esophagitis). If this condition is allowed to become chronic, it can in time develop into Barrett’s esophagus, which is the precursor of esophageal cancer.

Up to 15 million Americans experience acid reflux daily. People at all ages are susceptible to this condition. Older people who suffer from acid reflux tend to be more seriously affected than younger people. 13,000 people are diagnosed with esophageal cancer each year. At least 12,000 people die from it. The overall survival rate is very poor. Acid reflux is the greatest known risk factor for developing Barrett’s Esophagus, which can become esophageal cancer.

Barrett’s esophagus occurs when chronic acid reflux or esophagitis is not controlled. Through constant inflammation and damage, the normal cells that line the esophagus called squamous cells turn into specialized columnar cells. Columnar cells are not normally found in human beings and can become cancerous.

Although this can happen to anyone, it usually occurs in people over forty who have had regular bouts of heartburn for more than five years. Some of the symptoms are difficulty in swallowing and being awakened in the night by the pain of heartburn. Some people have no symptoms at all.

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